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Cushing syndrome, adrenal suppression and local corticosteroid use
Author(s) -
Hameed Rubina,
Zacharin Margaret R
Publication year - 2006
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2006.00880.x
Subject(s) - medicine , cushingoid , corticosteroid , dexamethasone , complication , adrenal cortex hormones , arthritis , adrenal crisis , cushing syndrome , adrenal insufficiency , shock (circulatory) , intra articular , adrenal disorder , pediatrics , pathology , alternative medicine , osteoarthritis , insulin resistance , glucose homeostasis , insulin
Abstract: Adrenal suppression can occur following use of intra‐articular corticosteroid injection for treatment of arthritis. If unrecognised, this can result in major medical illness, shock or death. We report two children who developed Cushingoid features and severe adrenal suppression after joint injection. Paediatricians caring for children who have intra‐articular corticosteroid injections should be aware of this potential complication. Monitoring of cortisol levels after injection should be considered.