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POLYMERIC CORE‐SHELL NANOPARTICLES FOR THERAPEUTICS
Author(s) -
Yang YiYan,
Wang Yong,
Powell Ross,
Chan Peggy
Publication year - 2006
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.2006.04408.x
Subject(s) - nanotechnology , nanoparticle , gene delivery , drug delivery , peptide , computational biology , chemistry , materials science , gene , biology , biochemistry , genetic enhancement
SUMMARY1 Nanobiotechnologies have recently attracted significant attention from chemists, biologists, engineers and pharmaceutical scientists. In particular, they have been widely applied to improve drug, protein/peptide and gene delivery. 2 This review presents recent advances in the field of drug, protein/peptide and gene delivery using natural and synthetic polymer nanoparticles and explains how polymeric nanoparticles are specifically designed to suit the needs for targeted delivery of small molecular drugs, proteins/peptides and genes. In addition, some of the challenges and prospects for these technologies are discussed.