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Efficacy of factor VIII/von Willebrand factor concentrate Alphanate ® in preventing excessive bleeding during surgery in subjects with von Willebrand disease
Author(s) -
RIVARD G. E.,
ALEDORT L.
Publication year - 2008
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1111/j.1365-2516.2007.01616.x
Subject(s) - medicine , von willebrand disease , von willebrand factor , perioperative , blood product , surgery , platelet
Summary. The adequacy of perioperative haemostasis with a high‐purity, plasma‐derived factor VIII product containing von Willebrand factor was retrospectively evaluated in 39 patients with type 1, 2 or 3 von Willebrand disease who underwent 61 major or minor surgical or invasive procedures. Overall, 93.5% of the responses to treatment were rated as excellent or good by the physician investigators. These ratings were confirmed by an independent panel of physician referees.