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A case of focal dermal hypoplasia (Goltz) syndrome with exophytic granulation tissue treated by curettage and photodynamic therapy
Author(s) -
Mallipeddi R.,
Chaudhry S. I.,
Darley C. R.,
Kurwa H. A.
Publication year - 2006
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2005.02007.x
Subject(s) - medicine , curettage , pyogenic granuloma , cryotherapy , granulation tissue , photodynamic therapy , surgery , dermatology , electrosurgery , cryosurgery , wound healing , lesion , chemistry , organic chemistry
Summary Focal dermal hypoplasia (Goltz) syndrome is a rare genetic disorder characterized by cutaneous, ectodermal and mesodermal defects. We present a case in which painful, exophytic granulation tissue has been the main symptom over the past 15 years. After unsatisfactory results with a number of treatment modalities including topical steroids, silver‐nitrate applications, cryotherapy, curettage, excision and pulsed‐dye laser, we achieved significant benefit with curettage in combination with photodynamic therapy. Although impaired wound healing has been described in focal dermal hypoplasia, this is, to our knowledge, the first time that pyogenic granuloma‐like lesions have been reported.