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Diagnosis and management of chronic graft‐versus‐host disease
Author(s) -
Dignan Fiona L.,
Amrolia Persis,
Clark Andrew,
Cornish Jacqueline,
Jackson Graham,
Mahendra Prem,
Scarisbrick Julia J.,
Taylor Peter C.,
Shaw Bronwen E.,
Potter Michael N.
Publication year - 2012
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.2012.09128.x
Subject(s) - medicine , guideline , graft versus host disease , refractory (planetary science) , disease , chronic disease , intensive care medicine , surgery , pathology , biology , astrobiology
Summary A joint working group established by the Haemato‐oncology subgroup of the B ritish C ommittee for S tandards in H aematology ( BCSH ) and the B ritish S ociety for B one M arrow T ransplantation ( BSBMT ) has reviewed the available literature and made recommendations for the diagnosis and management of chronic graft‐versus‐host disease ( G v HD ). This guideline includes recommendations for the diagnosis and staging of chronic G v HD as well as primary treatment and options for patients with steroid‐refractory disease. The goal of treatment should be the effective control of G v HD while minimizing the risk of toxicity and relapse.