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Missense SNP of the MC1R gene is associated with plumage variation in the Gyrfalcon ( Falco rusticolus )
Author(s) -
Zhan X. J.,
Dixon A.,
Fox N. C.,
Bruford M. W.
Publication year - 2012
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2011.02263.x
Subject(s) - biology , plumage , melanism , genetics , heterozygote advantage , phenotype , albinism , single nucleotide polymorphism , gene , missense mutation , genotype , allele , polymorphism (computer science) , zoology
Summary A single nucleotide polymorphism ( MC1R : c.376A>G) in the MC1R gene was found to be highly correlated with pigment phenotype in the Gyrfalcon. Homozygous genotypes c.376GG and c.376AA were found to dominate the extreme white and dark plumage types respectively, and heterozygotes occurred mainly in intermediate phenotypes. However, some heterozygotes were associated with extreme phenotypes, indicating that melanism/albinism might also involve other loci.