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Cutaneous silica granuloma with generalized involvement of lymph nodes
Author(s) -
HOU Maihua,
ZHU Wenyuan,
YE Yuda
Publication year - 2011
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2011.01206.x
Subject(s) - granuloma , lymph , pathology , lymph node , giant cell , chin , epithelioid cell , inguinal lymph nodes , anatomy , medicine , immunohistochemistry
We report a case of cutaneous silica granuloma with generalized involvement of distal lymph nodes; no similar case has been reported in the published work. The 45‐year‐old man was a stonemason who had been incidentally sprayed with rock dust from a saw 22 years ago. The subject presented with nodules and erythematous areas on his face and chin. In addition, there was swelling in the cervical and inguinal lymph nodes. An excised lymph node had normal architecture with numerous non‐caseating epithelioid cell granuloma and silicotic nodules which contained scattered, multinucleated, giant cells. There were particles in the granuloma exhibiting birefringence under polarized light microscopy. Elemental X‐ray spectra of these lesions showed the presence of silica in these granulomas.