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Electron Microscopic Study of Langerhans Cell Histiocytosis
Author(s) -
Kobayashi Miwa,
Yamamoto Osamu,
Suenaga Yoshinori,
Asahi Masakazu
Publication year - 2000
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2000.tb02205.x
Subject(s) - langerhans cell histiocytosis , histiocytosis , electron microscope , pathology , physics , medicine , quantum mechanics , disease
Among the several forms of Langerhans cell histiocytosis (LCH), Letterer‐Siwe disease is the most acute disseminated multisystemic variant. The course of Letterer‐Siwe disease is usually rapid and fatal. We report here a cases of Letterer‐Siwe disease which showed a good response to chemotherapy. We also describe the unusual ultrastructural findings in the histiocyte‐like cells in this case.