Premium
Bactericidal activity of grass carp Ctenopharyngodon idella C9‐deficient serum against Aeromonas hydrophila
Author(s) -
Ji C.,
Li A. H.,
Xie J.,
Zhang D. F.,
Liu J. Y.
Publication year - 2011
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.2011.03129.x
Subject(s) - grass carp , aeromonas hydrophila , biology , lytic cycle , pathogen , microbiology and biotechnology , complement system , fish <actinopterygii> , aeromonas , antibody , bacteria , fishery , immunology , virus , genetics
Neutralizing complement C9 in grass carp Ctenopharyngodon idella sera with rabbit anti‐C9 sera against fish complement C9, demonstrated that bactericidal activity against Aeromonas hydrophila of the C9‐deficient fish sera was greatly impaired. These results indicated that the fish complement C9 plays a key role in pathogen killing through the lytic pathway.