Open AccessLong non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
Author(s) -
Kuai Le,
Jiang JingSi,
Li Wei,
Li Bin,
Yin ShuangYi
Publication year - 2022
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/iwj.13655
Subject(s) - medicine , long non coding rna , wound healing , diabetes mellitus , coding (social sciences) , clinical significance , bioinformatics , inflammation , downregulation and upregulation , diabetic neuropathy , pathology , surgery , gene , endocrinology , biology , biochemistry , statistics , mathematics
Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non‐coding RNA (ncRNA) that lack coding potential, long non‐coding RNAs (lncRNAs) have recently been reported to play a salient role in diabetic wound healing. Here, this review summarises the roles of lncRNAs in the pathology and treatments of diabetic wounds, providing references for its potential clinical diagnostic criteria or therapeutic targets in the future.