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Platypnoea–orthodeoxia syndrome as an uncommon cause of dyspnoea: a literature review
Author(s) -
Lombardi Marco,
Del Buono Marco G.,
Princi Giuseppe,
Locorotondo Gabriella,
Lombardo Antonella,
Vergallo Rocco,
Montone Rocco A.,
Burzotta Francesco,
Trani Carlo,
Crea Filippo,
Sanna Tommaso
Publication year - 2022
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.15669
Subject(s) - medicine , supine position , presentation (obstetrics) , intensive care medicine , position paper , pathophysiology , surgery , pathology
Platypnoea–orthodeoxia syndrome (POS) is an uncommon but challenging clinical condition characterised by positional dyspnoea (platypnoea) and arterial desaturation (orthodeoxia) in the upright position that improve in the supine position. Since its first description, many cases have been reported and many conditions have been associated with this syndrome. Herein, we review the clinical presentation, pathophysiology, diagnostic work‐up and management of patients with POS, aiming to increase the awareness of this often misdiagnosed condition.