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Background  Measuring temperature has always been a key observation in the diagnosis of infection. No studies have examined the usefulness of measuring temperature at the wrist to detect infection.    Aim  We sought to determine whether a watch measuring wrist temperature could accurately identify patients who are infected.    Methods  Prospective cross‐sectional pilot study of temperature monitoring in an unselected patients in a tertiary referral adult nephrology unit.    Results  One hundred and four data recording sessions revealed 88 useful data sets, with recording failures in the others. Patients were retrospectively classified as having no infection (Group A,  n  = 60), clinically diagnosed infection with less than 24 h of treatment with antibiotics (Group B,  n  = 5), and clinically diagnosed infection with greater than 24 h on antibiotics (Group C,  n  = 23). There was a significantly higher average maximum temperature in Group B (mean (SEM)) 38°C (0.6) compared with Groups A (36.1°C (0.1)) and C (36.3°C (0.3)). Based on receiver operating characteristics (ROC) a cut‐off temperature of ≥37.5°C gave sensitivity 80% and specificity 98%. Mean electrodermal activity was significantly higher in Groups B and C.    Conclusions  ROC of peripheral skin temperature measurements suggest that such a device may identify many patients requiring treatment for infection. This proof of principle study showed value in using a wearable device in the detection of infection and its potential as an early warning or monitoring device.

Monitoring skin temperature at the wrist in hospitalised patients may assist in the detection of infection