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The multifaceted role of cell cycle regulators in the coordination of growth and metabolism
Author(s) -
Huber Katharina,
MestresArenas Alberto,
Fajas Lluis,
LealEsteban Lucia C.
Publication year - 2021
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.15586
Subject(s) - cyclin dependent kinase , cell cycle , microbiology and biotechnology , biology , cell metabolism , kinase , cyclin , cell growth , restriction point , cell cycle protein , e2f , cell division , transcription factor , cell , biochemistry , gene
This review discusses how the control of proliferation and cell division by cell cycle regulators is also involved in the metabolic adaptive responses when cells need to produce energy. We describe how cell cycle regulators are involved in the control of metabolic pathways, in cell growth and the functionality of organelles including endolysosomes and mitochondria.