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Long‐term outcomes of status epilepticus: A critical assessment
Author(s) -
Sculier Claudine,
GaínzaLein Marina,
Sánchez Fernández Iván,
Loddenkemper Tobias
Publication year - 2018
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/epi.14515
Subject(s) - status epilepticus , outcome (game theory) , medicine , etiology , epilepsy , pediatrics , term (time) , intensive care medicine , psychiatry , physics , mathematics , mathematical economics , quantum mechanics
Summary We reviewed 37 studies reporting long‐term outcomes after a status epilepticus (SE) episode in pediatric and adult populations. Study design, length of follow‐up, outcome measures, domains investigated (mortality, SE recurrence, subsequent epilepsy, cognitive outcome, functional outcome, or quality of life), and predictors of long‐term outcomes are summarized. Despite heterogeneity in the design of prior studies, overall risk of poor long‐term outcome after SE is high in both children and adults. Etiology is the main determinant of outcome, and the effect of age or SE duration is often difficult to distinguish from the underlying cause. The effect of the treatment on long‐term outcome after SE is still unknown.