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Randomized trial of intravenous immunoglobulin maintenance treatment regimens in chronic inflammatory demyelinating polyradiculoneuropathy
Author(s) -
Kuitwaard K.,
Brusse E.,
Jacobs B. C.,
Vrancken A. F. J. E.,
Eftimov F.,
Notermans N. C.,
Kooi A. J.,
Fokkink W. J. R.,
Nieboer D.,
Lingsma H. F.,
Merkies I. S. J.,
Doorn P. A.
Publication year - 2021
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/ene.14501
Subject(s) - medicine , placebo , polyradiculoneuropathy , dosing , randomized controlled trial , rasch model , multifocal motor neuropathy , confidence interval , dose , chronic inflammatory demyelinating polyneuropathy , antibody , physical therapy , pediatrics , immunology , guillain barre syndrome , mismatch negativity , statistics , alternative medicine , mathematics , pathology , electroencephalography , psychiatry
More frequent lower dosing does not further improve the efficacy of intravenous immunoglobulin (IVIg) in stable IVIg‐dependent chronic inflammatory demyelinating polyradiculoneuropathy. More frequent lower dosing does lead to more stable serum immunoglobulin G levels but not to higher trough levels (Fig. 3).