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Aim  To assess the clinical performance and patient acceptance of HemaSpot™ blood collection devices as an alternative blood collection method.    Methods  Adult men and women with any type of diabetes, routinely carrying out self‐monitoring of blood glucose were recruited (n = 128). Participants provided a venous blood sample and prepared two HemaSpot dried blood spots, one at clinics and one at home. HbA 1c  analysis was by Tosoh G8 high‐performance liquid chromatography. Participants also completed a questionnaire.    Results  Strong linear relationships been HbA 1c  levels in dried blood spots and venous blood were observed and a linear model was fitted to the data. Time between dried blood spot preparation and testing did not impact the model. Participants were accepting of the approach: 69.2% would use this system if available and 60.7% would be more likely to use this system than going to their general practitioner.    Conclusions  The combination of a robust desiccating dried blood spot device, home sample preparation and return by post produces HbA 1c  data that support the use of a time‐independent linear calibration of dried blood spot to venous blood HbA 1c . A robust remote sample collection service would be valuable to people living with diabetes in urban areas who are working or house‐bound as well as those living in remote or rural locations.

HbA 1c determination from HemaSpot™ blood collection devices: comparison of home prepared dried blood spots with standard venous blood analysis