English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Aim  Neuroprotection trials for neonatal encephalopathy use moderate or severe disability as an outcome, with the  B ayley  S cales of  I nfant  D evelopment, Second Edition ( B ayley‐2)  I ndex scores of <70 as part of the criteria. The  B ayley  S cales of  I nfant and  T oddler, 3rd  D evelopment, Third Edition ( B ayley‐3) have superseded  B ayley‐2 and yield higher than expected scores in typically developing and high‐risk infants. The aim of this study, therefore, was to compare  B ayley‐2 scores and  B ayley‐3 scores in term‐born infants surviving neonatal encephalopathy treated with hypothermia.    Method  Sixty‐one term‐born infants (37 males, 24 females; median gestational age at birth 40wks, range 36–42wks; median birthweight 3280g, range 2295–5050) following neonatal encephalopathy and hypothermia had contemporaneous assessment at 18 months using the  B ayley‐2 and  B ayley‐3.    Results  The median  B ayley‐3  C ognitive  C omposite score was 7 points higher than the median  B ayley‐2  M ental  D evelopmental  I ndex ( MDI ) score and the median  B ayley‐3  M otor  C omposite score was 18 points higher than the median  B ayley‐2  P sychomotor  D evelopmental  I ndex ( PDI ) score. Ten children had a  B ayley‐2  MDI  of <70; only three children had  B ayley‐3 combined  C ognitive/ L anguage scores of <70. Eleven children had  B ayley‐2  PDI  scores of <70 and four had modified  B ayley‐3  M otor  C omposite scores of <70. Applying regression equations to  B ayley‐3 scores adjusted rates of severe delay to similar proportions found using  B ayley‐2 scores.    Interpretation  Fewer children were classified with severe delay using the  B ayley‐3 than the  B ayley‐2, which prohibits direct comparison of scores. Increased  B ayley‐3 cut‐off thresholds for classifying severe disability are recommended when comparing studies in this clinical group using  B ayley‐2 scores.

Comparison of B ayley‐2 and B ayley‐3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia