English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Aim  Strain elastography is a method for recording tissue hardness. Strain in different areas may be compared using strain ratio ( SR ). The aims of this study were to validate a previously proposed  SR  cut‐off value of 1.25 for differentiating adenocarcinomas from adenomas and to compare the performance of endorectal ultrasonography ( ERUS ), strain elastography and  MRI  in the same patients.    Method  A prospective evaluation of 120 consecutive patients with rectal neoplasia, using a predetermined elastography strain ratio cut‐off value, was performed to differentiate adenomas from adenocarcinomas.  ERUS  and  MRI  were performed according to standard routine at Haukeland University Hospital, defining T0 as adenomas and T1–T4 as adenocarcinomas. Subsequent histopathology was used as the reference standard.    Results  Histopathological evaluation revealed 21 adenomas and 99 adenocarcinomas. Sensitivity, specificity and accuracy (with 95%  CI ) were as follows:  ERUS : 0.96 (0.90–0.99), 0.62 (0.40–0.80) and 0.90 (0.83–0.94); elastography  SR : 0.96 (0.90–0.99), 0.86 (0.66–0.96) and 0.94 (0.88–0.97); and  MRI : 0.99 (0.94–1.00), 0.07 (0.00–0.31) and 0.87 (0.80–0.93).    Conclusion  This study confirms that the elastography  SR  assessment accurately differentiates sessile adenomas from adenocarcinomas.  SR  assessment has a superior ability to differentiate adenomas and adenocarcinomas when compared with  ERUS  and  MRI .  MRI  examination seems unable to recognize adenomas and should be interpreted with care when early‐stage rectal neoplasia is suspected.

Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas