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Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study
Author(s) -
Suzuki Kayoko,
Yagami Akiko,
Ito Akiko,
Kato Atsuko,
Miyazawa Hitoshi,
Kanto Hiromi,
Matsunaga Kayoko
Publication year - 2019
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.13105
Subject(s) - sodium thiosulfate , patch test , gold standard (test) , thiosulfate , medicine , sodium , surgery , gastroenterology , chemistry , inorganic chemistry , sulfur , immunology , organic chemistry , allergy
Background The proportion of positive test results with gold sodium thiosulfate included in a patch test panel (P‐GST) had been found to be greater than that with gold sodium thiosulfate 0.5% pet. by allergEAZE (A‐GST). Objectives To compare positive reactions to P‐GST and A‐GST, and to evaluate late reactions after the day (D) 7 reading. Methods A retrospective analysis was performed of 588 patients at participating departments (119 males; 469 females) who were patch tested with P‐GST and A‐GST in May 2015 to March 2016. Results Positive test reactions to P‐GST and A‐GST were observed in 15% and 6% of patients, respectively. Three patients reported a positive reaction occurring after the D7 reading. Conclusions Gold sodium thiosulfate often gives a positive reaction after 2 to 3 weeks, and, in such cases, the positive reaction may be sustained, so it is recommended to assess the reaction for up to 1 month after application.