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Epithelial pearl formation following tympanic membrane regeneration therapy using an atelocollagen/silicone membrane and basic fibroblast growth factor: Our experience from a retrospective study of one hundred sixteen patients
Author(s) -
Hakuba N.,
Hato N.,
Omotehara Y.,
Okada M.,
Gyo K.
Publication year - 2013
Publication title -
clinical otolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.914
H-Index - 68
eISSN - 1749-4486
pISSN - 1749-4478
DOI - 10.1111/coa.12164
Subject(s) - medicine , regeneration (biology) , silicone , fibroblast , retrospective cohort study , membrane , pearl , surgery , microbiology and biotechnology , biochemistry , chemistry , philosophy , theology , organic chemistry , in vitro , biology
Dear Editor, Tympanic membrane perforation is frequently encountered in outpatient otorhinolaryngology practice. We have introduced a treatment procedure to promote regeneration of the tympanic membrane and closure of perforations using an atelocollagen sponge/silicone membrane combined with human basic fibroblast growth factor that promotes wound healing.1,2 This report describes epithelial pearl formation following our outpatient-based tympanic membrane regeneration therapy.