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In order to quantify the levels of SARS‐CoV‐2‐specific IgM, IgA, and IgG antibodies, identify changes in them based on COVID‐19 severity, and establish the significance of combined antibody detection, a chemiluminescence method was used to detect the levels of SARS‐CoV‐2‐specific antibodies in COVID‐19 patients with different severity. We concluded that detection of SARS‐CoV‐2‐specific combined IgA–IgG antibodies is advantageous in diagnosing COVID‐19 and more attention should be paid to specific IgA.

clinical & experimental immunology

Characteristics and roles of severe acute respiratory syndrome coronavirus 2‐specific antibodies in patients with different severities of coronavirus 19