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Objective  An evaluation of the effect of chlorhexidine/ketoconazole shampoo baths on the flea control efficacy of indoxacarb applied topically to dogs.    Methods and Results  We randomly allocated 18 healthy mixed‐breed dogs to 3 groups: shampoo only; indoxacarb treated and medicated shampoo; and indoxacarb treated but not shampooed. Indoxacarb was administered on day 0 and dogs were shampooed on days 9 and 23. Dogs were infested with 100 adult  Ctenocephalides felis  initially 2 days before treatment and then weekly from days 7 to 28. Fleas were removed and counted 48 h post‐infestation.    Conclusion  Medicated shampoo use did not significantly reduce indoxacarb efficacy against  C .  felis .

Flea ( Ctenocephalides felis ) control efficacy of topical indoxacarb on dogs subsequently bathed with a chlorhexidine–ketoconazole shampoo