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PRO‐C3 and ADAPT algorithm accurately identify patients with advanced fibrosis due to alcohol‐related liver disease
Author(s) -
Madsen Bjørn S.,
Thiele Maja,
Detlefsen Sönke,
Kjærgaard Maria,
Møller Linda S.,
Trebicka Jonel,
Nielsen Mette J.,
Gudmann Natasja Stæhr,
Leeming Diana J.,
Karsdal Morten A.,
Krag Aleksander
Publication year - 2021
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/apt.16513
Subject(s) - medicine , algorithm , biomarker , fibrosis , fatty liver , gastroenterology , liver disease , prospective cohort study , liver fibrosis , liver biopsy , alcohol , disease , biopsy , computer science , biochemistry , chemistry
Alcohol is a main cause of preventable deaths and frequently leads to the development of alcohol-related liver disease. Due to the lack of diagnostics, patients are commonly diagnosed after developing clinical manifestations. Recently, the biomarker PRO-C3 was shown to accurately identify fibrosis due to non-alcoholic fatty liver disease.