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This study sought to identify a model that explains the relationship between psychosocial factors and chronic pain in female patients, and to explore all of these constructs in a single study and provide a more holistic examination of the overall psychosocial factors that female patients with chronic pain encounter.    Methods  Female patients with chronic pain ( n  = 147), aged 20–65 ( M  = 34.9 years,  SD  = 11.25), from an outpatient pain clinic completed a cross‐sectional self‐report questionnaire on anxiety, life events, personality, social support, and alexithymia. Data were analyzed by means of path analysis.    Results  The direct effect of anxiety on female patients with chronic pain was greatest among all the paths. Personality and alexithymia led to chronic pain in female patients only indirectly, mediated by life events. The personality factors of neuroticism and extraversion were associated positively with social support, which had an indirect effect on the influence of life events on chronic pain. However, alexithymia was associated negatively with social support, which had an indirect effect on the influence of life events on chronic pain.    Discussion  Our findings provide evidence that life events are a mediator in the relationship between personality, social support, alexithymia, and chronic pain in female patients.

Life events, anxiety, social support, personality, and alexithymia in female patients with chronic pain: A path analysis