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Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants
Author(s) -
Lund AnnaMy,
Löfqvist Chatarina,
Pivodic Aldina,
Lundgren Pia,
Hård AnnaLena,
Hellström Ann,
HansenPupp Ingrid
Publication year - 2020
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.15102
Subject(s) - medicine , breast milk , breast feeding , obstetrics , food science , physiology , pediatrics , biochemistry , chemistry
Aim Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants. Methods Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days. Results Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7‐27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z ‐scores for weight, length and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z ‐score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z ‐scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (mL/kg/d). Conclusion Unpasteurised MM was positively associated with longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.