Open AccessThirty years of mirena: A story of innovation and change in women’s healthcare
Author(s) -
GemzellDanielsson Kristina,
Kubba Ali,
Caetano Cecilia,
Faustmann Thomas,
LukkariLax Eeva,
Heikinheimo Oskari
Publication year - 2021
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.14110
Subject(s) - medicine , levonorgestrel , family planning , intrauterine device , clinical practice , health care , clinical research , developed country , gynecology , obstetrics , population , healthcare system , clinical trial , research methodology , family medicine , economic growth , environmental health , economics , pathology
Since its introduction in 1990, the levonorgestrel‐releasing intrauterine system (LNG‐IUS) has played a key role in shaping the healthcare landscape of women. Here we explore the development of the first LNG‐IUS (Mirena®) and the early clinical trials that demonstrated its potential. We highlight the contraceptive and therapeutic benefits of Mirena®, and discuss how clinical practice has been changed since the introduction of LNG‐IUS and other long‐acting reversible contraceptive methods. The history of Mirena® is rich in innovation and has also paved the way to the development of smaller intrauterine systems with lower hormone doses. Along with Mirena®, these newer LNG‐IUS contribute to improving contraceptive choices for women, allowing them to select the option that is right for them and that meets their needs no matter their age, parity or circumstances.