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Agminated Spitz naevi or metastatic spitzoid melanoma?
Author(s) -
Kester Marloes Sophia,
Eggen Celine,
Beishuizen Auke,
Kukutsch Nicole Ariane
Publication year - 2018
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12781
Subject(s) - medicine , spitz nevus , papule , lymph , melanoma , sentinel lymph node , lesion , pathology , dermatology , nevus , cancer , cancer research , breast cancer
the immune system in psoriatic patients, whereby T helper 17 cells or innate lymphoid cell 3 systems become overactive to compensate, even though the defect cannot be detected clinically. The Koebner phenomenon may explain some of the distribution of the plaques as the increased expression of an antimicrobial peptide, cathelicidin, in psoriatic lesional epidermis is one of the provoking causes of inflammatory cascades.