English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Summary  Understanding the genetic basis of variation in traits related to growth and fillet quality in Atlantic salmon is of importance to the aquaculture industry. Several growth‐related  QTL  have been identified via the application of genetic markers. The   IGF 1  gene is considered a highly conserved and crucial growth‐regulating gene in salmonid species. However, the association between polymorphisms in the   IGF 1  gene and growth‐related traits in Atlantic salmon is unknown. Therefore, in this study, regions of the Atlantic salmon   IGF 1  gene were sequenced, aligned and compared across individuals. Three  SNP s were identified in the putative promoter ( SNP 1,  g.5763G>T ; GenBank no.  AGKD01012745 ), intron 1 ( SNP 2,  g.7292C>T ; GenBank no.  AGKD01012745 ) and intron 3 ( SNP 3,  g.4671A>C ; GenBank no.  AGKD01133398 ) regions respectively. These  SNP s were genotyped in a population of 4800 commercial Atlantic salmon with data on several weight and fillet traits measured at harvest (at approximately 3 years of age). In a mixed model, association analysis of individual  SNP s,  SNP 1 and  SNP 3 were both significantly associated with several weight traits ( P  <   0.05). The estimated additive effect on overall harvest weight was approximately 35 and 110 g for  SNP s 1 and 3 respectively. A haplotype analysis confirmed the association between genetic variation in the   IGF 1  gene with overall body weight ( P  <   0.05) and fillet component traits ( P  <   0.05). Our findings suggest the identified nucleotide polymorphisms of the   IGF 1  gene may either affect farmed Atlantic salmon growth directly or be in population‐wide linkage disequilibrium with causal variation, highlighting their possible utility as candidates for marker‐assisted selection in the aquaculture industry.

animal genetics

Single nucleotide polymorphisms in the  insulin‐like growth factor 1  (  IGF 1 ) gene are associated with growth‐related traits in farmed Atlantic salmon