Open AccessPrimary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
Author(s) -
Archwamety Anita,
Ruangchiraurai Ruchira,
Akewanlop Charuwan,
Korphaisarn Krittiya
Publication year - 2022
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.14580
Subject(s) - medicine , lymphoepithelioma like carcinoma , immunotherapy , carcinoma , lymphoepithelioma , primary (astronomy) , oncology , pathology , immunology , radiation therapy , cancer , virus , nasopharyngeal carcinoma , epstein–barr virus , physics , astronomy
Here, we report a case of metastatic Epstein–Barr virus (EBV)‐related primary pulmonary lymphoepithelioma‐like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome to ICIs in the late‐line treatment of advanced PPLELC patients with programmed cell death‐ligand 1 (PD‐L1) expression.