Open AccessAutopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor
Author(s) -
Morimoto Toshiki,
Yamasaki Kei,
Shingu Tatsuya,
Sato Tomoki,
Uryu Takumu,
Jotatsu Takanobu,
Kato Kaori,
Kawabata Hiroki,
Nishida Chinatsu,
Yatera Kazuhiro
Publication year - 2022
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.14559
Subject(s) - medicine , autopsy , pathology , lung , lung cancer , large cell , carcinoma , adenocarcinoma , cancer
A 69‐year‐old Japanese man visited our hospital because of worsening shortness of breath. His chest computed tomography (CT) showed a giant left lung mass with a massive left pleural effusion. He could not be treated with chemotherapy and eventually died from a rapidly progressive tumor. He was diagnosed with combined small cell lung carcinoma (C‐SCLC) with spindle‐shaped cell tumor at autopsy. C‐SCLC is characterized by pathologically concurrent SCLC and adenocarcinoma or squamous cell carcinoma, or rarely, spindle‐shaped cell tumor. The clinical course of C‐SCLC with spindle‐shaped cell tumor has not previously been determined. Our patient's tumor increased by 2.59‐fold in 20 days. The combination of C‐SCLC with spindle‐shaped cell tumor suggested rapid progression and a poor prognosis.