Open AccessLow‐grade fibromyxoid sarcoma arising from the lung: A case report
Author(s) -
Yoshimura Ryuichi,
Nishiya Masao,
Yanagawa Naoki,
Deguchi Hiroyuki,
Tomoyasu Makoto,
Kudo Satoshi,
Shigeeda Wataru,
Kaneko Yuka,
Kanno Hironaga,
Sugai Mayu,
Shikanai Shunsuke,
Sugai Tamotsu,
Saito Hajime
Publication year - 2021
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.14107
Subject(s) - medicine , differential diagnosis , sarcoma , asymptomatic , malignancy , lung , radiology , pathology
Abstract Low‐grade fibromyxoid sarcoma (LGFMS) is a rare sarcoma subtype that most commonly arises in young adults. This tumor typically presents in the deep soft tissues of the proximal extremities or trunk as a painless mass. Although the most common site of LGFMS metastasis is the lung, it is rarely the primary site. Here, we report a case of primary pulmonary LGFMS. A 22‐year‐old asymptomatic man was referred to our hospital for investigation of a lung mass that had been discovered incidentally. Computed tomography (CT) showed a well‐defined mass 4.0 cm in diameter in the upper lobe of the right lung. Malignancy was suggested by focal uptake of 18F‐fluorodeoxyglucose positron‐emission tomography (18‐FDG‐PET). Following surgery, postoperative histological analysis of the resected specimen demonstrated LGFMS based on histological and immunohistological findings. In particular, mucin 4 showed diffuse positivity in the spindle‐shaped tumor cells. In conclusion, LGFMS can arise in the lungs, and physicians should consider this entity as a differential diagnosis for solitary lung mass in young adults.