Open AccessParaneoplastic E vans syndrome in a patient with adenocarcinoma of the lung: A case report
Author(s) -
Yu Hong,
Fu Rong,
Wang Huaquan,
Liu Hui,
Shao Zonghong
Publication year - 2017
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12398
Subject(s) - medicine , evans syndrome , adenocarcinoma , malignancy , lung cancer , lung , adenocarcinoma of the lung , chemotherapy , papillary adenocarcinoma , cancer , pathology , oncology , autoimmune hemolytic anemia , anemia
We present a rare case of newly diagnosed E vans syndrome associated with lung papillary adenocarcinoma in which the patient showed prompt restoration of blood cell count and long‐lasting complete remission of E vans syndrome after lung cancer resection. Detailed investigation led to a diagnosis of E vans syndrome. In the first year of the disease, left lower lung papillary adenocarcinoma was diagnosed. Pulmonary lobectomy and three courses of chemotherapy were performed. Six months after the initial visit, the primary lung cancer and the autoimmune diseases appeared to be well controlled. We hypothesized that our patient's initial presentation of hematological manifestation was a paraneoplastic phenomenon associated to her underlying malignancy. This rare case report illustrates the unique relationship between primary lung cancer and the development of paraneoplastic E vans syndrome.