Open AccessClinicopathological characteristics and prognosis of resected cases of carcinoid tumors of the lung
Author(s) -
Yang Zhi,
Wang Zitong,
Duan Yong,
Xu Shaofa
Publication year - 2016
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12377
Subject(s) - medicine , carcinoid tumors , univariate analysis , lymph node , lung , lung cancer , multivariate analysis , oncology , gastroenterology , radiology , pathology
Background Lung carcinoid tumors are rare, low‐grade, malignant neoplasms with some unclear features. T he aim of this study was to analyze clinicopathological features and long‐term survival in patients with primary lung carcinoid tumors. Methods Patients who underwent surgery in our clinic and were diagnosed with carcinoid tumors, between A ugust 1997 and J uly 2012, were included in the study. P atient characteristics and clinicopathological factors were retrospectively evaluated. Results Bronchial carcinoids comprised only 1.0% of lung cancer cases treated by resection. They are classified into two distinct categories: typical carcinoid ( TC ) and atypical carcinoid ( AC ) tumors. AC tumors occurred more frequently in younger patients and in smokers, and had a poorer prognosis than TC tumors . Overall three and five‐year survival rates for TC and AC were 92.6% and 81.1%, respectively. Univariate analysis showed that t umor size ( P = 0.012) and histological type ( P = 0.013) are prognostic factors. Multivariate analysis revealed that only tumor size ( P = 0.044) was an independent prognostic factor. Conclusions The prognosis for bronchial carcinoid t umors was better than other types of lung cancer and TC was significantly better than AC . Radical lymph node dissection was the best treatment, with complete removal of the tumor. Tumor size was an independent prognostic factor for bronchial c arcinoid t umors.