Open AccessGiant mediastinal thymolipoma in a patient with G ardner's syndrome
Author(s) -
Pei Guotian,
Han Yi,
Zhou Shijie,
Liu Zhidong
Publication year - 2015
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12231
Subject(s) - medicine , penetrance , thoracotomy , variable expression , mediastinum , pathology , surgery , gene , biochemistry , chemistry , phenotype
Gardner's syndrome is a hereditary disorder inherited as an autosomal dominant with high penetrance and variable expression that is caused by a mutation of the adenomatous polyposis coli gene. It is characterized by gastrointestinal polyps associated with multiple osteomas, dental anomalies, and skin and soft tissue tumors. We present a case of 30‐year‐old female patient with G ardner's syndrome who presented with a giant mediastinal thymolipoma. The tumor was completely excised through a bilateral posterolateral thoracotomy. There was no recurrence after 20 months of follow‐up. We therefore suggest that physicians who regularly treat patients with G ardner's syndrome carefully examine for thoracic manifestations.