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Background  The prevalence of symptomatic knee osteoarthritis ( KOA ) in Singapore is unknown. We aimed to: (i) validate questionnaires to screen for symptomatic  KOA ; and (ii) estimate the prevalence of symptomatic  KOA  in Singapore using the validated algorithms.    Methods  Subjects aged ≥50 years were evaluated for symptomatic  KOA  based on American College of Rheumatology clinical and radiographic criteria in a rheumatology clinic, and completed three sets of adapted screening questionnaires. The better performing screening questionnaire with adequate sensitivity and specificity was adminitered to a nationally representative sample of survey subjects ( n  = 3364) to estimate the weighted prevalence of symptomatic  KOA  in Singapore.    Results  Out of 146 subjects evaluated in the clinic, 45 had symptomatic  KOA . A screening algorithm which consisted of three  KOA  symptoms or one symptom plus physician‐diagnosed  KOA  produced high specificity (0.95, 95% confidence intervals [ CI ]: 0.88–0.98) but low sensivity (0.44, 95%  CI : 0.30–0.60). Replacing the term ‘ KOA ’ with ‘physician‐diagnosed ageing‐related knee problem’ improved the sensivity (0.62, 95%  CI : 0.47–0.76) without significantly compromising the specificity (0.87, 95%  CI : 0.79–0.93). The prevalence of symptomatic  KOA  weighted to the Singapore population distribution were 4.7% and 11%, using the most conservative and more liberal algorithms, respectively. There was a sharp rise in prevalence after age of 40. The weighted prevalence of  KOA  was higher in women and among Indian and Malay than Chinese.    Conclusion  Our study adapted and validated questionnaires to the local context to screen for symptomatic  KOA . We estimated the prevalence of symptomatic  KOA  in Singapore utilizing the better‐performing algorithms.

Validation of screening questionnaires for evaluation of knee osteoarthritis prevalence in the general population of Singapore