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The medical field is witnessing rapid adoption of artificial intelligence (AI) and machine learning (ML), revolutionizing disease diagnosis and treatment management. Researchers explore how AI and ML can optimize medical decision-making, promising to transform healthcare. Feed Forward Neural Networks (FNN) are widely used to create predictive disease models, cross-validated by medical experts. However, complex medical data like diabetes leads to multi-modal search spaces prone to local minima, affecting optimal solutions. In this study, we focus on optimizing a diabetes dataset from the Pima Indian community, evaluating decision-making performance in diabetes management. Employing multimodal datasets, we compare various optimization algorithms, including the Whale Optimization Algorithm (WOA) and Particle Swarm Optimization (PSO). The test results encompass essential metrics like best-fit value, mean, median, and standard deviation to assess the impact of different optimization techniques. The findings highlight the superiority of the Oppositional Whale Optimization Algorithm (OWOA) over other methods employed in our research setup. This study demonstrates the immense potential of AI and metaheuristic algorithms to revolutionize medical diagnosis and treatment approaches, paving the way for future advancements in the healthcare landscape. Results reveal the superiority of OWOA over other methods. AI and metaheuristics show tremendous potential in transforming medical diagnosis and treatment, driving future healthcare advancements.

FNN for diabetic prediction using oppositional whale optimization algorithm