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Introduction to molecular replacement: a time perspective
Author(s) -
Dodson Eleanor
Publication year - 2021
Publication title -
acta crystallographica section d
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.374
H-Index - 138
ISSN - 2059-7983
DOI - 10.1107/s2059798321004368
Subject(s) - phaser , molecular replacement , perspective (graphical) , computer science , software , management science , operations research , engineering , chemistry , programming language , artificial intelligence , crystal structure , crystallography , electrical engineering
This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix.