Open AccessIn vivo physiological saline‐infused hepatic vessel imaging using a two‐crystal‐interferometer‐based phase‐contrast X‐ray technique
Author(s) -
Takeda Tohoru,
Yoneyama Akio,
Wu Jin,
Momose Atsushi,
Hyodo Kazuyuki
Publication year - 2012
Publication title -
journal of synchrotron radiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 99
ISSN - 1600-5775
DOI - 10.1107/s0909049511056226
Subject(s) - in vivo , saline , contrast (vision) , vein , angiography , tail vein , materials science , portal vein , hepatic portal vein , biomedical engineering , nuclear medicine , medicine , radiology , optics , biology , physics , microbiology and biotechnology
Using a two‐crystal‐interferometer‐based phase‐contrast X‐ray imaging system, the portal vein, capillary vessel area and hepatic vein of live rats were revealed sequentially by injecting physiological saline via the portal vein. Vessels greater than 0.06 mm in diameter were clearly shown with low levels of X‐rays (552 µGy). This suggests that in vivo vessel imaging of small animals can be performed as conventional angiography without the side effects of the presently used iodine contrast agents.