Open AccessICTV Virus Taxonomy Profile: Hepadnaviridae
Author(s) -
Lars O. Magnius,
William S. Mason,
John M. Taylor,
Michael Kann,
Dieter Glebe,
Paul Dény,
Camille Sureau,
Heléne Norder
Publication year - 2020
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/jgv.0.001415
Subject(s) - biology , virology , genome , reverse transcriptase , polymerase , dna , polymerase chain reaction , genetics , gene
The family Hepadnaviridae comprises small enveloped viruses with a partially double-stranded DNA genome of 3.0-3.4 kb. All family members express three sets of proteins (preC/C, polymerase and preS/S) and replication involves reverse transcription within nucleocapsids in the cytoplasm of hepatocytes. Hepadnaviruses are hepatotropic and infections may be transient or persistent. There are five genera: Parahepadnavirus , Metahepadnavirus , Herpetohepadnavirus, Avihepadnavirus and Orthohepadnavirus . This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepadnaviridae, which is available at ictv.global/report/hepadnaviridae.