Open AccessValproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells
Author(s) -
Nancy M Archin,
Joseph J. Eron,
Sarah Palmer,
Anne Hartmann-Duff,
Jeffery A Martinson,
Ann Wiegand,
Nicholas Bandarenko,
John L. Schmitz,
Ronald J. Bosch,
Alan Landay,
John M. Coffin,
David M. Margolis
Publication year - 2008
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3282fd6df4
Subject(s) - valproic acid , human immunodeficiency virus (hiv) , medicine , virology , lentivirus , antiretroviral therapy , immunology , viral disease , viral load , epilepsy , psychiatry
Valproic acid and intensified antiretroviral therapy may deplete resting CD4+ T-cell HIV infection. We tested the ability of valproic acid to deplete resting CD4+ T-cell infection in patients receiving standard antiretroviral therapy.