Open Access422.4: Defective Mitophagy in Aged Macrophages Promotes Mitochondrial DNA Cytosolic Leakage to Activate STING Signaling During Liver Ischemia and Reperfusion Injury
Author(s) -
Yu Sun,
Weizhe Zhong,
Zhuqing Rao,
Jian Xu,
Haoran Hu,
Xuehao Wang
Publication year - 2022
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000887904.21953.97
Subject(s) - mitophagy , microbiology and biotechnology , mitochondrion , pink1 , cytosol , biology , parkin , sting , signal transduction , autophagy , cancer research , medicine , apoptosis , biochemistry , disease , aerospace engineering , parkinson's disease , engineering , enzyme