Open AccessEffects of Long-term Administration of High-dose Recombinant Human Antithrombin in Immunosuppressed Primate Recipients of Porcine Xenografts
Author(s) -
Emanuele Cozzi,
Paolo Simioni,
M Boldrin,
M Seveso,
Fiorella Calabrese,
N Baldan,
Roberto Busetto,
Daniela Tormene,
Sabrina Gavasso,
Massimo Castagnaro,
Yann Echelard,
Tim Rice,
Mario Plebani,
Paolo Carraro,
Erika Bosio,
Marialuisa Valente,
Antonio Pagnan,
Gaetano Thiene,
Ermanno Ancona
Publication year - 2005
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000178377.55615.8b
Subject(s) - fibrin , antithrombin , coagulopathy , xenotransplantation , transplantation , immunology , non human primate , primate , anticoagulant , biology , medicine , heparin , surgery , neuroscience , evolutionary biology
Fibrin deposition is central to the acute humoral rejection process occurring in the presence of consumptive coagulopathy when pig organs are transplanted into primates.