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Effect of Barley Sprout Water Extracts on Blood Flow Improvement in vitro
Author(s) -
Lee Dasom,
Kwon Han Ol,
Lee Minhee,
Park Soojeung,
Kim Hyesook,
Kim Ki Man,
Choi Byungkuk,
Choi Dabin,
Lee Jeongmin
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.966.14
Subject(s) - chemistry , thromboxane b2 , partial thromboplastin time , platelet , thromboxane , prothrombin time , endocrinology , medicine , hordeum vulgare , biology , botany , poaceae
Barley sprout ( Hordeum rulgare L .) is believed to have effect of antioxidant, metabolism of lipid, anti‐cancer and depression of formation fatty liver. However, the benefits of the barley sprout to blood flow improvement have not been studied yet. The purpose of this study was to investigated the effect of barley sprout water extract efficacy of blood flow improvement in vitro of serotonin secretion, Thromboxane A2 secretion, platelet aggregation, activited partial thromboplastin time, prothrombin time, shear stress induced platelet aggreagation, and sgear stress induced micorvesicle generation. Serotonin secretion was significantly decreased in the 400 μg/mL as compated with 0 μg/mL. Thromboxane A2 secretion from phospholipid membrane was significantly decreased in the 400 μg/mL as compated with 0 μg/mL. Platelet aggreation was significantly decreased in the 400 μg/mL as compated with 0 μg/mL. Activatied partial thromboplastin time in plasma was significantly increased in the 400 μg/mL as compated with 0 μg/mL. Prothrombin time in plasma was non significantly. Shear stress induced platelet aggregation was significantly decreased in the 400 μg/mL as compated with 0 μg/mL. Shear stress induced microvesicle generation in human erythrocytes were significantly decreased in the 400 μg/mL as compated with 0 μg/mL. In conclusion, these result suggest that Barley sprout water extracts 400 μg/mL administration ha ameliorated the blood flow.