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Mechanism of Non Point Source(S) causing Antibiotic ‐ Resistance in Infectious Diseases
Author(s) -
Kannan Subburaj,
Martinez Juan,
Montoya Hector,
Barrera Jorge,
Cooley Roy,
Orozco Maria,
Villanueva Brenda
Publication year - 2013
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.27.1_supplement.1037.1
Subject(s) - antibiotics , antibiotic resistance , agriculture , staphylococcus aureus , environmental health , medicine , ecology , biology , microbiology and biotechnology , bacteria , genetics
Self medication, sharing of medication, prescribing antibiotics for viral infection, not completing the dosage, failure to complete the prescribed dosage and excessive use of antibiotics in industrial farming practices, and priming effects are serious public health concerns. Run‐off water from agricultural land and toxic aerosol originating from the recent oil exploration in this region constitute potential Non Point Source for chemical contaminants. The pesticides, suspended sediments, and fertilizers into estuarine habitats adjacent to agricultural areas or downstream from agricultural watersheds may potentially contaminate the aquifer. Subsequent consumption of contaminated water by humans and animal subjects has been has been shown to cause tissue toxicity. Community origin of MRSA (patients with open sores taking bath in common bath tub in the rehabilitation centers), and nosocomial infections are striking realities of this region. Recreational beaches in Southwest Texas, the Gulf coast, and flanking coastal towns in Mexico are a potential non‐point source as reservoir for MRSA (Methicillin‐resistant Staphylococcus aureus). Collectively, aforesaid factors have resulted in a dramatic selection pressure on microbial pathogens carrying antibiotic resistance genes. The inherent nature of AR induced tissue toxicity pose considerable challenges in treating infectious diseases.