Open AccessReirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival
Author(s) -
Christopher H. Chapman,
Jared Hara,
Annette M. Molinaro,
Jennifer Clarke,
Nancy Ann Oberheim Bush,
Jennie Taylor,
Nicholas Butowski,
Susan M. Chang,
Shan Fogh,
Penny K. Sneed,
Jean L. Nakamura,
David R. Raleigh,
Steve Braunstein
Publication year - 2019
Publication title -
neuro-oncology practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 14
eISSN - 2054-2585
pISSN - 2054-2577
DOI - 10.1093/nop/npz017
Subject(s) - medicine , radiosurgery , salvage therapy , radiation therapy , overall survival , toxicity , oncology , surgery , chemotherapy
Optimal techniques and patient selection for salvage reirradiation of high-grade glioma (HGG) are unclear. In this study, we identify prognostic factors for freedom from progression (FFP) and overall survival (OS) after reirradiation, risk factors for high-grade toxicity, and validate clinical prognostic scores.