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Source/Description: The probe pE0.8 is a 0.8 kb EcoRI genomic fragment subcloned in pUC13 and isolated from a cosmid containing human chromosome 19 sequences homologous to the excision repair gene, ERCC1. The ERCC1 gene has been shown to be located within 250 kb telomeric to the CKM gene (Smeets et al. 1990). Human DNA sequences contained in pE0.8 correspond to a genomic region approximately 15 kb centromeric to exon 1 of the ERCC1 gene (Shutler et al., 1991).

An insertion polymorphism identified by the probe pE0.8 (D19S115) at 19q13.3