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Plasmablastic lymphoma of the rectum: case report of a rare location and literature review
Author(s) -
Razan Saleh AlMohamedi,
Waleed A. AlRajban,
Ammar C. AlRikabi,
Maha Arafah
Publication year - 2022
Publication title -
journal of surgical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.14
H-Index - 3
ISSN - 2042-8812
DOI - 10.1093/jscr/rjac030
Subject(s) - plasmablastic lymphoma , medicine , lymphoma , immunohistochemistry , presentation (obstetrics) , rectum , pathology , epstein–barr virus , aggressive lymphoma , human immunodeficiency virus (hiv) , stain , virus , immunology , staining , radiology , rituximab
Plasmablastic lymphoma (PBL) is an aggressive and rare variant of diffuse large B-cell lymphoma, which is thought to occur in immunocompromised individuals, specifically HIV-positive patients. We report the case of a 27-year-old Saudi male with PBL. The patient had a low CD4 count at presentation, however, he was HIV negative at the time of diagnosis; also Human herpesvirus-8 was negative on immunohistochemical stain, but Epstein–Barr virus showed expression in scattered cells through the utilization of EBV-EBER.

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