Open AccessEvolution of Antibodies to Epitopes of PE_PGRS51 in the Spectrum of Active Pulmonary Tuberculosis
Author(s) -
Rama Murthy Sakamuri,
Michelle B. Ryndak,
Krishna K. Singh,
Suman Laal
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz546
Subject(s) - epitope , antibody , tuberculosis , biology , antibody repertoire , in vivo , mycobacterium tuberculosis , virology , homology (biology) , immunology , medicine , genetics , amino acid , pathology
Intrafamily homology has impeded correlation of expression of individual PE_PGRS proteins with stage of tuberculosis (TB). We investigated the in vivo expression of PE_PGRS51, which has 3 unique regions.