Open AccessRandomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL) – Rationale and Study Protocol
Author(s) -
Ruth Masterson Creber,
Monika M. Safford,
Karla V. Ballman,
Annie Myers,
Stephen E. Fremes,
Mario Gaudino
Publication year - 2021
Publication title -
european heart journal. quality of care and clinical outcomes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.766
H-Index - 18
eISSN - 2058-5225
pISSN - 2058-1742
DOI - 10.1093/ehjqcco/qcab022
Subject(s) - medicine , quality of life (healthcare) , randomized controlled trial , physical therapy , angina , mental health , sf 36 , clinical trial , health related quality of life , surgery , myocardial infarction , psychiatry , nursing , disease
The objective of the Randomized comparison of the Outcome of single vs. Multiple Arterial grafts: Quality of Life (ROMA:QOL) trial is to evaluate the impact of coronary artery bypass graft surgery (CABG) on quality of life (QOL). The primary hypothesis of ROMA:QOL is that participants in the multiple arterial graft (MAG) will report time-varying changes in QOL that will be lower in the post-operative recovery period and higher after 12 months compared to patients in the single arterial graft (SAG). The secondary hypotheses are that both groups will have improvements in symptoms at 12 months, and that compared to the SAG group, participants in the MAG group will experience better physical functioning and physical and mental health symptoms.