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Sir,Noseda and colleagues (2016) report findings from a very informative multifaceted study aimed at exploring the effect of different light wavelengths in eliciting photophobia in patients with migraine, and probing the basis for any differential effect. They found that green light exacerbated headache significantly less than white, blue, amber or red lights. They went on to show, using electroretinography and visual evoked potentials in patients, that green light stimuli produce less activation of cone-driven pathways, discernible at the level …

Pupil area and photopigment spectral sensitivity are relevant to study of migraine photophobia